Prospective Assessment of Helicobacter Pylori Infection and Gastric Pathologies in Sidi Bel Abbes region, Western Algeria

Authors

  • Zouaouia Chama Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria
  • Khedoudj Kanoun Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria
  • Fatima Zohra Elkadi Biotoxicology Laboratory Department of Biology, Djillali Liabes University, Sidi bel Abbes, Algeria
  • Kara Turqui Douidi Gastro Enterology Department, University Hospital of Sidi bel Abbes region, Western Algeria
  • Noria Harir Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria
  • Mohamed Kerkoud DIAG-GENE Laboratory, Angers Cedex, France
  • Bouziyane Abbouni Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

DOI:

https://doi.org/10.38150/sajeb.7(5).p217-224

Abstract

Helicobacter pylori infection concerns half of the world’s population, mainly in developing countries. It causes several gastrodudenal pathologies such as gastritis, ulcer and gastric adenocarcinoma. The aim of our study was to determine the prevalence of H.pylori infection and to assess the impact of different epidemiological factors as well as principal gastric diseases associ-ated to this infection. We underwent a prospective study during 18 months (month 2016-month 2017) which implicated 201 symptomatic patients for gastric fiboptic endoscopy at the level of Sidi Bel Abbes University hospital. We collected patients’ biopsies to perform a histological study and H. pylori culture. H. pylori identification was carried out based on bacteriological and biochemical analysis. The middle age of our population was (47.29 ±15.97ans) and the sex-ratio =0,8. The global prevalence of Helicobacter pylori infection is of 61.2% (123/201). This rate, after a statistic analysis, seems to be significantly related to age. It is particularly high especially for patients belonging to age range (20-30)-(51-60) years. The gender did not affect the infection prevalence that is more frequent in the gastritis case. We noticed also that HP infection prevalence was important in SBA the hospital. The range age (20-30)-(51-60) years had the highest prevalence of H. pylori and of gastritis which might be a risky ground of gastric cancer appearance. The ulcer pathology maximal rate concerned the group of 51 to 60 years. Above this age, this rate dropped whereas the number of patients suffering from gastric cancer, which presents an important rate in our study, increase for the group of 61-70 years.

Author Biographies

Zouaouia Chama, Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

Khedoudj Kanoun, Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

Fatima Zohra Elkadi, Biotoxicology Laboratory Department of Biology, Djillali Liabes University, Sidi bel Abbes, Algeria

Biotoxicology Laboratory Department of Biology, Djillali Liabes University, Sidi bel Abbes, Algeria

Kara Turqui Douidi, Gastro Enterology Department, University Hospital of Sidi bel Abbes region, Western Algeria

Gastro Enterology Department, University Hospital of Sidi bel Abbes region, Western Algeria

Noria Harir, Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

Mohamed Kerkoud, DIAG-GENE Laboratory, Angers Cedex, France

DIAG-GENE Laboratory, Angers Cedex, France

Bouziyane Abbouni, Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

Molecular Microbiology Proteomics and Health Laboratory, Department of Biology, Faculty of Natural Sciences and Life, Djillali Liabes University, Sidi Bel Abbes, Algeria

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Published

2018-07-09

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Section

Research Articles