Molecular detection and epidemiology of chicken infectious anaemia virus in India

Abstract

Chicken infectious anemia (CIA) is an economically important disease affecting poultry, especially young chicks, characterized by poor weight gain, anemia, immunosuppression and production losses. Recent reports indicate that the virus is emerging and re-emerging worldwide.  Also, scarce reports regarding the molecular detection and epidemiology of virus from India are available. The aim of this study was to determine the prevalence of the virus in the commercial poultry farms of the country employing polymerase chain reaction (PCR). Out of the suspected 424 field samples tested from 12 different states of the country during the last five years (2007-2012), 311 (73.3%) samples were found positive for CIAV-DNA indicating the wide prevalence of the virus in India. The age wise prevalence of the virus indicated high prevalence in young chicks of up to three weeks (80.3%) of age compared to 3-7 (66.6%) and 7-12 (25%) week age groups. Being an immunosuppressive emerging pathogen circulating among the poultry flocks of the country, suitable prevention and control measures need to be adopted timely. This is a first elaborative report on the molecular epidemiology of CIAV in poultry flocks of the country. Extensive epidemiological studies are suggested to know the magnitude of the virus affecting poultry industry of the country, and design and formulate effective disease prevention and control strategies to reduce economic losses being caused by emerging virus.